Knowledge Management System adalah pengelolaan pengetahuan yang meningkatkan kompetensi SDM dengan optimasi jalur komunikasi knowledge pada organisasi. Perguruan Tinggi perlu mengupayakan kualitas dosen. KMS ini menyebarkan pengetahuan di antara dosen, diujicobakan pada Universitas Indraprasta, Jakarta, dengan temuan: informasi bahan ajar lambat, dosen harus menguasai banyak mata kuliah, penguasaan mata kuliah dosen berbeda-beda, belum ada sistem informasi komputer pengelola pengetahuan, dan pemanfaatan TIK pada KM belum optimal. Penelitian dengan model kerangka Amrit Tiwana. Pengujian dengan FGD, 4 karakteristik model ISO 9126 (functionality, reliability, usability, dan efficiency), dan WAPT. Hasil: prototipe KMS berbasis web dengan fitur utama: input data dosen, mata kuliah; forum diskusi; memuat dan mengunduh berkas, pencarian berkas.
Kata Kunci: Knowledge, Knowledge Management System, Perguruan Tinggi, Model
Tiwana, Model Zack, FGD, ISO 9126.

Knowledge Management System is managing knowledge to increase the competence of human resources with the communication path optimization knowledge to the organization. Universities need to seek the quality of lecturers. KMS is to spread knowledge among professors, tested at the University Indraprasta, Jakarta, with the findings: information teaching materials is slow, lecturers must master many subjects, mastery of the course lecturers are different, there is no computer information systems managers the knowledge and use of ICT in KM is not optimal. Research by Amrit Tiwana framework model. Testing with FGD, 4 ISO 9126 model characteristics (functionality, reliability, usability, and efficiency), and WAPT. Result: a prototype web- based KMS main features: data input lecturer, course; discussion forum; load and download a file, the file search.
Keywords: Knowledge, Knowledge Management System, Universities, Tiwana Model, Model Zack, FGD, ISO 9126.