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Novel synthetic chemistry of ureas and amides

In this thesis, the author investigates the chemistry and application of molecules containing urea and amide bonds. These bonds are some of the strongest known and are fundamental to biological processes. The author describes his discovery that sterically hindered ureas undergo solvolysis at room temperature under neutral conditions. This is a remarkable finding, since ureas are inert under these conditions and a general rule of chemistry is that hindered substrates are less reactive. Remarkably, the author translates these results to the correspondingly sterically hindered amides. This thesis has resulted in a number of outstanding publications in high profile journals. The unique method for breaking urea and amide bonds developed in this study is likely to have far reaching consequences for biological protein manipulation.

Ketersediaan
#
Perpustakaan Pusat E257
E257
Tersedia
Informasi Detail
Judul Seri
Springer Theses
No. Panggil
E257
Penerbit
Berlin : Springer Berlin.,
Deskripsi Fisik
XVIII, 166 Hlm.
Bahasa
English
ISBN/ISSN
9783642320514
Klasifikasi
NONE
Tipe Isi
text
Tipe Media
computer
Tipe Pembawa
online resource
Edisi
1
Subjek
Kimia Organik
Katalisis
Info Detail Spesifik
-
Pernyataan Tanggungjawab
Versi lain/terkait

Tidak tersedia versi lain

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