Electronic Resource

Studying cell metabolism and cell interactions using microfluidic devices coupled with mass spectrometry

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This thesis describes a new approach for cell analysis by the rapid developing microfluidic technology. The nominee has made great contributions to develop a new analysis platform which combined microfluidic devices with mass spectrometry to determine the trace compounds secreted by cells. Based on this analysis platform, she studied the specific cell secreting behaviors under controlled microenvironment, of which the secretion compounds were qualified and semi-quantified by mass spectrometry. A novel cell sorting device integrated homogenous porous PDMS membrane was invented to classify cells from real samples based on the size difference. The nominee further studied the signal transmission between different cells, and the signal chemicals were qualitative and quantitative monitored by the analysis platform. This indicates the potential significant application of the new cell analysis platform in medicine screening and early diagnosis.

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Ketersediaan

Informasi Detail

Judul Seri

Springer theses

No. Panggil

E260

Penerbit

Berlin : Springer Berlin., 2012

Deskripsi Fisik

XVI, 104 Hlm.

Bahasa

English

ISBN/ISSN

9783642323591

Klasifikasi

NONE

Tipe Isi

text

Tipe Media

computer

Tipe Pembawa

online resource

Edisi

1

Subjek

Nanotechnology and Microengineering
Mass Spectrometry
Cell Biology

Info Detail Spesifik

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Pernyataan Tanggungjawab

Huibin Wei

Versi lain/terkait

Lampiran Berkas

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